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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPR
All Species:
17.58
Human Site:
T1372
Identified Species:
42.96
UniProt:
P12270
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12270
NP_003283.2
2363
267293
T1372
T
K
R
I
Q
Q
L
T
E
E
I
G
R
L
K
Chimpanzee
Pan troglodytes
XP_514063
2363
267281
T1372
T
K
R
I
Q
Q
L
T
E
E
I
G
R
L
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537167
2427
273798
T1436
T
K
R
I
Q
Q
L
T
E
E
I
G
R
L
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_598541
2431
273972
N1446
T
K
R
I
Q
Q
L
N
E
E
V
G
R
L
K
Rat
Rattus norvegicus
NP_001100655
2360
267287
N1372
T
K
R
I
Q
Q
L
N
E
E
V
G
R
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516826
2360
266175
T1373
T
K
R
I
Q
Q
M
T
E
E
T
G
R
L
K
Chicken
Gallus gallus
XP_422300
2368
267561
S1375
T
K
R
I
Q
Q
M
S
E
E
T
G
R
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001025294
2352
265963
V1375
L
K
R
I
Q
Q
L
V
E
E
T
G
R
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477067
2346
262334
V1351
R
Q
R
A
N
A
L
V
E
K
S
N
R
N
P
Honey Bee
Apis mellifera
XP_395964
2218
250206
P1262
E
R
A
N
K
T
S
P
E
D
W
R
R
L
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
94.2
N.A.
91.2
94.2
N.A.
87.9
83.8
N.A.
58.9
N.A.
20.1
24.1
N.A.
N.A.
Protein Similarity:
100
99.8
N.A.
95.8
N.A.
94.2
97.3
N.A.
94.3
92
N.A.
77.6
N.A.
42.9
46.2
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
86.6
80
N.A.
80
N.A.
26.6
20
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
80
N.A.
40
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
100
80
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
80
0
0
0
0
0
0
30
0
0
0
0
% I
% Lys:
0
80
0
0
10
0
0
0
0
10
0
0
0
0
80
% K
% Leu:
10
0
0
0
0
0
70
0
0
0
0
0
0
90
0
% L
% Met:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
20
0
0
0
10
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% P
% Gln:
0
10
0
0
80
80
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
10
90
0
0
0
0
0
0
0
0
10
100
0
0
% R
% Ser:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% S
% Thr:
70
0
0
0
0
10
0
40
0
0
30
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
20
0
0
20
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _